Peptide Lexicon

Thymosin Alpha-1

Thymosin Alpha-1 in the T&T Supplies peptide lexicon: research reference with mechanism, reported effects, limitations and literature data. Evidence grade B.

Mechanism

Endogenous peptide originally isolated from thymic tissue. Enhances T-cell, NK cell, and dendritic cell function. Upregulates IL-2, IFN-γ. Activates Toll-like receptors. Promotes antigen presentation. Anti-inflammatory via IL-10 pathway.

Reported effects

Immune system enhancement and normalization. Antiviral effects. Used clinically for immunocompromised patients. Strong safety data from approved medical use. Potential benefit post-illness or during intense training phases.

Limitations

Healthy young with normal immune function may see minimal benefit. Expensive. Primary benefit for immunocompromised or sick individuals. Mild injection site reactions.

Literature data

Dosage (literature)

1-2mg subcut 2×/week. Clinical dose: 1mg/m² body surface area

Timing

Any time — immune timing less critical

Cycling

2-6 week cycles. Or as needed during illness

Information for research purposes only.