Peptide Lexicon

TB-500

TB-500 in the T&T Supplies peptide lexicon: research reference with mechanism, reported effects, limitations and literature data. Evidence grade C+.

Mechanism

Synthetic fragment of thymosin beta-4. Binds G-actin → cell migration/differentiation. Integrin-linked kinase activation. Metalloproteinase upregulation for tissue remodeling. Vascular tube formation.

Reported effects

Systemic healing (reaches distant injury sites). Muscle fiber regeneration. Flexibility/ROM improvements. Potential cardiac protection.

Limitations

Human RCT data absent for recovery use. Higher MW limits oral bioavailability. More expensive than BPC-157. Overlap with BPC-157.

Literature data

Dosage (literature)

Loading: 2-2.5mg 2×/week × 4-6 weeks. Maintenance: 2-2.5mg 1×/week

Timing

Morning or post-training

Cycling

6-week loading, then maintenance or off

BPC-157 + TB-500 in the shop

Information for research purposes only.