Peptide Lexicon

SS-31

SS-31 in the T&T Supplies peptide lexicon: research reference with mechanism, reported effects, limitations and literature data. Evidence grade B-.

Mechanism

Tetrapeptide that concentrates in inner mitochondrial membrane, stabilizing cardiolipin. Binds cardiolipin → stabilizes electron transport chain structure. Reduces mitochondrial ROS production. Maintains cristae morphology. Improves ATP synthesis efficiency.

Reported effects

Mitochondrial function restoration. Reduced oxidative stress. Improved energy efficiency (not stimulant-based). Potential muscle function improvement. Active pharmaceutical development — human safety data exists.

Limitations

Expensive per mg. Mostly disease-state human trials — healthy young data absent. Injectable only (high MW). Long-term use unknown.

Literature data

Dosage (literature)

1-5mg/day subcut. Clinical trials used 0.05-0.25 mg/kg IV

Timing

Morning

Cycling

4-12 week cycles. Research ongoing

Information for research purposes only.