Peptide Lexicon

Semax

Semax in the T&T Supplies peptide lexicon: research reference with mechanism, reported effects, limitations and literature data. Evidence grade B+.

Mechanism

Upregulates BDNF. Modulates dopaminergic/serotonergic transmission. Increases enkephalinase activity. NO signalling enhancement.

Reported effects

Enhanced focus, memory, learning. Neuroprotection. Anti-anxiety via serotonin. Rapid onset 15-30 min. No physical dependence.

Limitations

Receptor desensitization — cycling required. Mild anxiety at high doses. Most studies Russian literature.

Literature data

Dosage (literature)

0.5–1mg/day intranasal

Timing

Morning, fasted or first meal

Cycling

5 days ON / 2 OFF. Or 3 weeks ON / 1 week OFF

Semax in the shop

Information for research purposes only.