Peptide Lexicon

Selank

Selank in the T&T Supplies peptide lexicon: research reference with mechanism, reported effects, limitations and literature data. Evidence grade B.

Mechanism

Allosteric GABA-A modulation. Inhibits enkephalinase. Modulates BDNF/NGF. Complements Semax via distinct brain connectivity patterns.

Reported effects

Anxiolysis without sedation or dependence. Cognitive enhancement. Anti-inflammatory. Low desensitization risk at standard doses.

Limitations

Most evidence Russian studies. Additive CNS depression with other GABAergics — critical interaction. Short half-life ~2h intranasal.

Literature data

Dosage (literature)

250–800mcg/day intranasal

Timing

Morning or 30-60 min before stressful situations

Cycling

14 days ON / 14 days OFF, or situational

Information for research purposes only.