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Peptide Lexicon

Epithalon

Epithalon in the T&T Supplies peptide lexicon: research reference with mechanism, reported effects, limitations and literature data. Evidence grade C+.

Mechanism

Synthetic tetrapeptide from the pineal gland. Claimed telomerase activator. Activates telomerase (hTERT) in somatic cells. Regulates melatonin secretion. Antioxidant. Regulates hypothalamic-pituitary axis.

Reported effects

Telomere elongation in elderly subjects. Normalizes melatonin in aged individuals. Sleep improvement. Antioxidant effects.

Limitations

Studied mainly in elderly subjects. Abnormally long telomeres have been associated with higher tumor risk. Single research group with patent conflict.

Literature data

Dosage (literature)
5-10mg/day × 10-20 days (elderly protocol)
Timing
Evening
Cycling
2× per year for elderly users

Information for research purposes only.