Peptide Lexicon

AHK-Cu

AHK-Cu in the T&T Supplies peptide lexicon: research reference with mechanism, reported effects, limitations and literature data. Evidence grade C+.

Mechanism

Tripeptide analogue of GHK-Cu with higher affinity for hair follicle receptors. Activates Wnt/β-catenin pathway in hair follicles. Upregulates VEGF in follicle microvasculature.

Reported effects

Hair density and thickness improvement. Potentially superior to GHK-Cu for scalp applications. Can be used topically or subcut. Anti-inflammatory in follicle microenvironment.

Limitations

Less research than GHK-Cu overall. Mostly in-vitro data. Higher cost per mg. Limited human studies specifically.

Literature data

Dosage (literature)

Topical: 0.01-0.1% solution on scalp. Subcut: 1-2mg/day

Timing

Evening or post-shower for topical

Cycling

Continuous or 8-week cycles

Information for research purposes only.